The Specificity of Pepsin
نویسنده
چکیده
منابع مشابه
Transformation of Swine Pepsinogen into Swine Pepsin by Chicken Pepsin
Activation of swine pepsinogen with chicken pepsin results in the formation of swine pepsin. Activation of chicken pepsinogen with swine pepsin results in the formation of chicken pepsin. The structure responsible for the species specificity of the enzyme is therefore present in the inactive precursor.
متن کاملDemonstration of Pepsin Activity in Circulating Immune Complexes Isolated from Diabetic Patients
Pepsin activity was demonstrated in circulating immune complexes, isolated from sera of 90 diabetic patients, which included 30 type 1, 60 type 2 diabetic patients and 40 control subjects, by the polyethylene glycol method. Pepsin activity was estimated by the proteolytic assay, using acidified haemoglobin as substrate. The mean polyethylene glycol indices in type 1 and type 2 diabetic patients...
متن کاملSpecificity of immobilized porcine pepsin in H/D exchange compatible conditions.
Statistical analysis of data from 39 proteins (13 766 amino acid residues) digested with immobilized porcine pepsin under conditions compatible with hydrogen/deuterium (H/D) exchange (<1 degrees C, <30 s) was performed to examine pepsin cleavage specificity. The cleavage of pepsin was most influenced by the amino acid residue at position P1. Phe and Leu are favored residues each with a cleavage...
متن کاملImmunochemical Studies on the Components of the Pepsinogen System
Rabbit antisera to pepsin and pepsinogen were characterized by several immunological criteria. Both antisera inhibited the rennet activity of pepsin. Antipepsinogen protected pepsin from alkaline denaturation. Using antipepsinogen, precipitin analysis at pH 5.5 indicated that the native enzyme resembles the precursor more closely than did the denatured enzyme. However, all three proteins have s...
متن کاملStudies of Human Anti-γ-globulin Factors Reacting with Pepsin-digested Γ-globulins
Many sera from normal individuals as well as patients with various disease states contain agglutinating antibodies which show specificity for antigenic determinants of gamma-globulin revealed by pepsin digestion at pH 4.1. Sera containing such agglutinating activity as well as sera negative for these agglutinators contain low molecular weight (3S-5S) components of slow gamma-mobility which inhi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003